Moreover, bioinformatics tools identified interactions between cancer-related miRNAs miR-141-3p/miR-200a-3p and circRNA_100395, and target genes of the hsa_circRNA_100395/miR-141-3p/miR-200a-3p axis such as E2F3, CCND2, CCNG1, CDC25B, GLS, PTEN, and ZFPM2 [105]. The gene discussed is GLS; the disease is cancer.