Several characteristics of the GluN2D subunit, including peak expression early in development, its localization to PV+ interneurons in the cortex and hippocampus and, additionally, reports of alterations to this subunit in post-mortem tissue from people with schizophrenia, and evidence of GRIN2D being a schizophrenia candidate gene, suggest that it may be involved in schizophrenia pathology. This evidence concerns the gene GRIN2D and schizophrenia.