As a whole group, urinary MALAT1 and CASC2 levels were significantly increased in lupus nephritis compared to healthy controls (31.3 [IQR 21.5–61.9] vs. 9.3 [IQR 9.2–11.5] copies and 18.4 [IQR12.2–156.0] vs. 9.9 [IQR 9.7–12.1] copies, respectively; p < 0.0001 for both). Here, CASC2 is linked to lupus nephritis.