CRP and alkaline phosphatase measurement: Although there was no statistically significant difference at baseline CRP values (3.9 (8.3;1.7) vs. 4.5 (11.7;1.5) mg/dL; p = 0.456), a significantly higher value after 30 days in the higher initial AP drop cohort was observed (2.1 (5.7;0.7) vs. 4.6 (10.6;1.8) mg/dL; p = 0.001).