Based on the molecular aspects of the inclusions in neurons and glial cells, FTD neuropathology can be divided into three main groups: TDP-43 (about 50% of cases), tau (about 40%), and FET, including FUS, EWSR1 (Ewing sarcoma breakpoint region 1/EWS RNA binding protein 1), and TAF15 (TATA-box-binding protein-associated factor 15), accounting for 10% of cases [127,128]. The gene discussed is TARDBP; the disease is frontotemporal dementia.