HIF1A and renal cell adenocarcinoma: The alignment of polymorphisms related to RCC susceptibility and HIF-1 binding sites was observed in a genome-wide association study using chromatin immunoprecipitation sequencing (CHIP-Seq), in which it was found that rs12814794 single nucleotide polymorphisms (SNP) at chr 12p12.1 were related to RCC susceptibility.