This study revealed increased levels of WBC, monocytes, IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, M1 profile, and anti-inflammatory profile, indicating heightened proinflammatory as well as anti-inflammatory activity in ASD adolescents, and increased PDW, IL-1β, IL-6, TNF-α, M1 profile, proinflammatory profile, and proinflammatory/anti-inflammatory ratio indicating dominant proinflammatory activity in ADHD adolescents. Here, IL6 is linked to attention deficit-hyperactivity disorder.