TNNI3 and amyotrophic lateral sclerosis: We have recently shown that cTnT, arguably reflecting neuromuscular involvement, but not cTnI, is commonly increased in the serum of patients with ALS, correlating with clinical severity as measured using the revised ALS Functional Rating Scale (ALSFRS-R) and thus could be of utility to distinguish the disease from ALS mimics or other neurodegenerative diseases [9].