SIRT1 and Hyperglycemia: For hypo- and normoglycemic conditions, the decrease of SIRT1 concentration in the BC was observed only after 24 h of RSV administration (time point 36 h) (to equal 43% and 64% comparing to the respective values at time point 12 h), whereas for hyperglycemia, the SIRT1 concentration decreased substantially after 12 h of RSV administration (to 16% at time point 24 h comparing to time point 12 h), and then greatly increased (to 58% at time point 36 h comparing to time point 12 h).