PTEN and cirrhosis of liver: Likewise, miR-1237-5p targets PTCH1, ITGA5, and LRP1 genes, which are associated with “cirrhosis of the liver”, “fibrosis of the liver”, “glucose metabolism disorder”, and “production of reactive oxygen species in the liver”, and with the NAFLD-related canonical pathway’s “hepatic fibrosis signaling pathway”, “PI3K/AKT signaling”, and “PTEN signaling” [73].