In the Xiantao database, higher SERPINA1 expression was connected to better overall survival (OS) in BRCA (breast invasive carcinoma), COAD (colon adenocarcinoma), DLBC, KIRC, KIRP, osteosarcoma, SARC (sarcoma), and SKCM (skin cutaneous melanoma) (Figure 3A–H). The gene discussed is SERPINA1; the disease is osteosarcoma.