The GEPIA database was utilized to replenish the analysis of cancers without corresponding normal tissues, and the results showed that SERPINA1 expression was overexpressed in most cancers except ACC (adrenocortical carcinoma), DLBC (lymphoid neoplasm diffuse large B-cell lymphoma), and THYM (thymoma) (Figure 1B). The gene discussed is SERPINA1; the disease is adrenal cortex carcinoma.