The TIMER database confirmed that SERPINA1 mRNA expression was significantly higher in BLCA (bladder urothelial carcinoma), HNSC (head and neck squamous cell carcinoma), KIRC (kidney renal clear cell carcinoma), KIRP (kidney renal papillary cell carcinoma), STAD (stomach adenocarcinoma), THCA (thyroid carcinoma), and UCEC (uterine corpus endometrial carcinoma) than in paired normal tissues. The gene discussed is SERPINA1; the disease is bladder transitional cell carcinoma.