The results of a study conducted on 92 patients (66 with ischemic stroke) in which NT-proBNP was assessed within 72 h after stroke showed a cut-off of 265.5 pg/mL, sensitivity and specificity in diagnosing cardioembolic stroke of 71.4% and 73.7% respectively with AUC values = 0.77 [55]. This evidence concerns the gene NPPB and cardioembolic stroke.