MiRNAs could have a role in cancerogenesis because miR-125b directly targets proapoptosis genes blocking their function and leading to uncontrolled cell proliferation; as far as gastric cancer treatment is concerned, in vivo and in vitro experiments have been conducted using bicalutamide, an antagonist of androgen receptor involved in the pathogenesis of the disease. The gene discussed is AR; the disease is gastric cancer.