PPP1R3C and colorectal carcinoma: For colorectal carcinoma, two different studies reported distinct roles of PPP1R3C: on one hand, it is linked to an aggressive phenotype following its methylation [37]; on the other, coherent with data from TCGA (Figure S3), it is reported to be poorly methylated, and its consequent overexpression correlates with a higher proliferation of colon cancer cells [38].