We detected 24 genes across the tumor tROIs that showed a high CV (i.e., were among the genes with the top 20% highest CV in seven out of seven cases), such as multiple collagens (COL1A1, COL1A2, COL3A1, COL5A1, COL5A2), S100A8, S100A9, FN1, or Early growth response protein 1 (EGR1) (Figure S5b). Here, COL5A2 is linked to neoplasm.