Indeed, a comparison between tumor and NAT regions resulted in a multitude of differentially expressed proteins and genes, some of which were identified at both the proteome and transcriptome level and were also supported by the CPTAC pADC dataset [6], such as the upregulation of ALDOA and MUC1, or the downregulation of A2M and COL6A6. Here, A2M is linked to neoplasm.