NPHS1 and focal segmental glomerulosclerosis: Recently, we investigated the relationship between podocyte injury and GM3 and demonstrated that in healthy subjects, GM3 colocalizes with nephrin, which plays an important role in the glomerular filtration barrier, whereas there was an inverse correlation between albuminuria levels and not only nephrin but also GM3 expression levels in patients with minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) due to podocyte injury [17].