TNF and cancer: The KEGG pathway revealed that GADD45A and GADD45B with the co-expression genes were mainly enriched in the TNF signaling pathway (p = 3.36 × 10−7), the MAPK signaling pathway (p = 2.68 × 10−7), the IL-17 signaling pathway (p = 3.18 × 10−7), transcriptional mis-regulation in cancer (p = 4.36 × 10−7), and the NF-κB signaling pathway (p = 5.28 × 10−7) (Figure 6B).