TNF and inflammatory skin disease: Next, the putative anti-inflammatory effects of DMG-Na were assessed on cultured human HaCaT keratinocytes stimulated with the combination of 25 ng/mL of interferon-γ (INFγ) + 25 ng/mL of TNFα, a well-established in vitro model of inflammatory skin diseases including, but not limited to, psoriasis [36,53].