NFKB1 and pulmonary emphysema: In our study, we showed that pep-BbKI and dexamethasone were able to attenuated the hyperresponsiveness to methacholine, some inflammatory cells, reduction of extracellular cellular matrix remodeling, oxidative stress markers, and NF-κB-positive cells in the airways and alveolar septa in a model of allergic pulmonary inflammation and elastase-induced emphysema overlap (ACO model).