EVs from patients suffering from glioblastoma (GBM) are capable to polarize CD14+ and CD163+ monocytes toward the M2 anti-inflammatory phenotype, enhancing blood serum concentrations of colony-stimulating factor 2 and 3, as well as to detect interleukin-2, -4, and -13 [114]. The gene discussed is IL2; the disease is glioblastoma.