Thrombophilia screening was performed in 18 cases (75%); major thrombogenic polymorphisms were detected in six cases (33.3%) (Factor V Leiden Mutation n = 2, Lupus anticoagulant n = 1, Methylenetetrahydrofolate (MTHFR) mutation n = 3). The gene discussed is MTHFR; the disease is Rare hereditary thrombophilia.