Genetic testing confirmed inherited thrombophilia, with positive Factor V Leiden, Factor V A4070G (HR2 haplotype), MTHFR A1298C, PAI-1 4G/5G promoter, Factor XIII (Val34Leu) and Fibrinogen 455 G>A heterozygous gene mutations. The gene discussed is F5; the disease is Rare hereditary thrombophilia.