Our group has shown that fractalkine and its receptor, CX3CR1, are involved in recruiting effector memory T cells to the myocardium during MI [55], and our unpublished pilot data suggest this could also be true in HF; patients with reduced LVEF one year after MI display lower CX3CR1 fluorescence in effector memory T cells. Here, CX3CR1 is linked to myocardial infarction.