PDE5A and Priapism: Prescribed drugs causing priapism reported mostly in adults comprise antipsychotics (chlorpromazine, olanzapine, quetiapine, trazadone), PDE-5 inhibitors (sildenafil), anti-depressants, anti-hypertensives (including a-blockers), and depot testosterone, while illicit drugs also encountered in teenagers are cocaine, ecstasy, and marijuana [25,95].