Wada et al. [21] retrospectively analyzed 23 patients with NV-AMD who underwent rescue PDT and reported that the number of anti-VEGF injections decreased from 5.8 times/year before rescue PDT to 2.6 times/year after PDT; central macular thickness improved from 319 μm to 226 μm and the VA changed from 0.16 to 0.11, which is not significant. This evidence concerns the gene VEGFA and age-related macular degeneration.