Following univariate analysis, the predictors of bacterial pneumonia were as follows: COVID-19 vaccination status; recent hospitalization; obesity; CHD; non-cardiac vasculopathy; chronic kidney disease (CKD); CCI, SAPS II, and SOFA score; pre-ICU length of stay; MDR colonization; neutrophils count; procalcitonin (PCT) and C-reactive protein (CRP) values; and total Brixia score. Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.