FGFR2 and gastric cancer: IHC staining for FGFR2 isoform IIb (FGFR2b) strongly correlates with FGFR2 copy number changes with high sensitivity and specificity [120], making IHC for FGFR2b a rapid and efficient screening tool to stratify patients with GC who may benefit from FGFR2-targeted therapy [120].