In humans, MITF mutations are reported to be associated with Waardenburg syndrome [28]; Tietz albinism deafness syndrome (TADS) [29,30]; coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness (COMMAD) [31]; non-syndromic hearing loss [32]; and melanoma and renal carcinoma [33]. Here, MITF is linked to microphthalmia.