Two variants (IL6 rs1800795 and rs1800797) were found in high LD and were therefore considered together during data synthesis; the meta-analysis from three studies (n = 1432) assessing these variants did not demonstrate significant association between the common allele and AD risk (OR (95% CI): 1.08 (0.89–1.31); I2 = 16.7%). This evidence concerns the gene IL6 and Alzheimer disease.