The L138ins variant was detected in 7 (0.33%) individuals (0.163% of the examined chromosomes), including four patients with azoospermia in the heterozygous state, one patient with CBAVD in the compound heterozygous state (genotype F508del/L138ins, 9T/7T), and in two infertile men (one patient with azoospermia and one patient with asthenozoospermia) in the combination with the 5T (IVS9T5) allele of CFTR gene [6]. This evidence concerns the gene CFTR and Infertility.