CFTR and cystic fibrosis: We found two pathogenic CF-causing variants in the CFTR gene in eight patients, seven of which were compound heterozygous (F508del/L138ins, n = 4; F508del/N1303K, n = 1; 2184insA/E92K, n = 1; 3849+10kbC>T/E92K, n = 1) and one was homozygous (L138ins/L138ins).