MMP8 and Sepsis: Especially, Mmp3 was upregulated in both septic induction models (Figure 3E), similarly for several other Mmp family genes, including Mmp2, Mmp8, Mmp9, Mmp14, and Mmp17, which were upregulated in both models of sepsis, whereas Mmp11, Mmp15, Mmp19, and Mmp17 did not fully upregulate in CLP septic induction in comparison with LPS septic induction (Figure 3E).