Most classic PTC cases (BRAF-like) were diagnostic from routine FNAB, yet profiles picked up via indeterminate biopsies, including occasional differentiated thyroid carcinomas (DTC), which include PTC, FTC, and oncocytic thyroid carcinoma (OTC), largely included genetic RAS-like variants and those that were NBNR. Here, BRAF is linked to differentiated thyroid carcinoma.