RPS6KB1 and breast cancer: Additionally, we reported that glycated albumin, belonging to the heterogeneous group of advanced glycation end-products (AGEs), increased the phosphorylation of p70S6K1 (phospho-p70S6K1) 25-fold within 10 min in a highly invasive breast cancer MDA-MB-231 cell line (a MSL TNBC model) while most of the signaling protein phosphorylation enhanced by 5–7.5-fold, suggesting phospho-p70S6K1 as a potential biomarker for breast cancer progression in diabetic conditions [227].