Shakhanova et al. [130] analyzed the association between polymorphism of LPL (lipoprotein lipase), ADRB2 (β2-adrenergic receptor), AGT (angiotensinogen), and AGTR1 (angiotensin II type 1 receptor) genes with risk of hyperinsulinism and insulin resistance in a case-control study that included 460 subjects aged 18 to 65 from the Kazakh population. Here, ADRB2 is linked to Insulin resistance.