Using independent test data, this approach yielded a mean AUC of 0.7400 [0.5041, 0.9326] and a mean AUPRC of 0.8582 [0.6737, 0.9695] on average (100 cycles), demonstrating high performance in discriminating IDH wild-type from IDH mutated gliomas. This evidence concerns the gene IDH2 and glioma.