LPS-TLR4 enhances the production of numerous mediators associated with inflammatory responses [7,10,11], e.g., IL-6, TNF-α, IL-8, IL-1, and CRC progression, e.g., VEGFC, MMP2, MMP9, ICAM-1, VCAM-1 [10,12,13]. This evidence concerns the gene TLR4 and colorectal carcinoma.