Dilated cardiomyopathy (DCM) is characterized by an expanded left ventricle with a thinned ventricular wall and impaired contractility, and is often associated with mutations in sarcomere genes such as TPM1, TNNT2 and MYH7 (Myosin Heavy Chain 7) [46]. Here, MYH7 is linked to familial dilated cardiomyopathy.