To fulfill this purpose, histopathological and IHC analyses for the expression of NKX2-1 and SCGB3A2 were carried out in lung tumors from aging B6;129 mice and from 10- to 16-week-old CC10TAg transgenic mice, which express SV40 large T antigen under the mouse Scgb1a1 (Clara cell-specific 10-kDa protein, CC10) gene promoter. Here, SCGB1A1 is linked to Neoplasm of the lung.