SPI1 and Alzheimer disease: Beyond APOE, we can mention other genes related to microglial dysfunction in AD: ABCA7, ABI3/NESH, ADAM10, ALPK2, BIN1, CASS4, CD33, CLU, CR1, HLA-DRB1, INPP5D/SHIP1, MS4A6A, PICALM, PLCG2, SORL1, SPI1/PU.1, TREM2 [27] and LILRB2 [216] (we suggest consulting www.brainrnaseq.org, last accessed on 15 June 2023, and Zhang Y. et al. [217] for better insight into human cell type expression, AlzPedia (Alzforum.org) and Hansen DV et al. [218] for direction and putative function of these genes).