Specifically, vascular endothelial growth factor C (VEGF-C) and its receptor VEGFR-3, which is also known as Fms-like tyrosine kinase 4 (FLT4), are expressed in tumor cells and associated with growth of blood vessels within tumors, as well as the progression of cancer cells to other parts of the body and the overall prognosis of the disease. Here, FLT4 is linked to neoplasm.