However, in contrast to several investigations that focused on the effects of TGF-β-1 and TGF-β-2 on the pathogenesis of glaucoma using HTM cells [32,61,62] and conjunctival fibrosis [37,38,46,47,63,64,65], the influence of TGF-β-3 has not been extensively investigated so far. This evidence concerns the gene TGFB2 and glaucoma.