Considering that, in patients with ICMP, the content of MMP-9 and EDCs in the sinus blood was higher than that in the peripheral blood and, in CHD patients without cardiomyopathy, it was found to be equal (Table 2), the MMP-9 hypersecretion in the myocardium probably indicates its angiodestructive effect. Here, MMP9 is linked to coronary artery disorder.