Because it is difficult to measure each biomarker individually, and no tubular marker has been recognized as a standard biomarker for DKD screening, non-albumin proteinuria (NAP), which can be calculated by subtracting urinary albumin from total protein, has been introduced as an accessible tubular marker that includes a wide range of biomarkers for tubular injury [57]. The gene discussed is ALB; the disease is diabetic kidney disease.