PTPRC and liver dysplastic nodule: To capture the gene expression changes in specific macrophage cell subsets in DN we performed a scRNA-seq analysis of CD45-enriched kidney immune cells from type 1 diabetic OVE26 mice at two time points (3 and 7 months, respectively) during the DN progression and performed a detailed analysis of mononuclear phagocytes in the diabetic kidney (Figure 2) [25].