DDIT3 and Stroke: In the stroke BCAO animal model, we found that Carb greatly reduced the size of the brain infarction (Figure 9c) and markedly improved the functional outcome at the molecular/cellular level, including a decrease in ER stress markers GRP 78 (Figure 9a) and CHOP (Figure 9b), and at behavioral levels, such as a decrease in asymmetric turns (Figure 9g,h) and an increase in locomotor activity (Figure 9e,f).