IL6 and appendicitis: In turn, the analysed initial concentrations of IL-6 were significantly (p = 0.018, and p = 0.036, respectively) higher in children with symptoms of appendicitis compared to the group with no inflammation before the surgery, performed with both laparoscopic and open method (Me of 6.99 vs. 2.66 and 14.79 vs. 2.55, respectively) (Table 3).