CRP and metabolic syndrome: A cross-sectional study including 14.493 children aged from 5 to 18 years old showed that a rise in WHR was substantially linked with an increase in cardio-metabolic risk in overweight and obese participants: of obese children with a WHR ≥ 0.6, 32% had metabolic syndrome, 26% had raised non-HDL-c levels, 18% had elevated C-reactive protein levels, and 69% had elevated HOMA-IR values [86].