CRP and Sepsis: Figure 4 shows boxplots of CRP levels and MHLA-DR expression in septic and non-septic patients. To predict the development of sepsis, optimal cut-offs were CRP level > 106.90 mg/mL (74.19% sensitivity, 69.49% specificity), MHLA-DR expression rate < 72.80% (45.31% sensitivity, 89.47% specificity), and an MFI of MHLA-DR < 1882 (73.53% sensitivity, 53.76% specificity).