To investigate the mechanisms through which PA induces its chemotactic effects in lung cancer, the cells were challenged with an optimal concentration of the phospholipid that causes the maximal stimulation of cell migration, and then the phosphorylation levels of ERK1-2, JNK, and p38, which are major kinases implicated in malignant transformation, were determined [1]. The gene discussed is MAPK8; the disease is lung carcinoma.