Over a 2-year period, the presence of a single engorged CAML was associated with 20.9 times increased likelihood of progression (<i>p</i> = 0.016) in non-metastatic PCa, and 2.4 times likelihood of progression (<i>p</i> = 0.031) with 5.4 times likelihood of death (<i>p</i> < 0.001) in metastatic PCa. Here, CAMLG is linked to posterior cortical atrophy.